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Glabridin is the main compound in the hydrophobic fraction of licorice extract. It is known for its beneficial effects on the skin due to its anti-inflammatory and antioxidant properties. In addition, glabridin inhibits melanogenesis. Some researchers have established that this effect may be due to the inhibition of tyrosinase activity.

 

Glabridin is a bio-available isoflavan isolated from licorice (Glycyrrhiza glabra L.) root extract. Glabridin has been reported to posses varies biological activities including strong antioxidant activity, antioxidant against LDL oxidation, anti-Helicobacter pylori properties, estrogen-like activity and antinephritic and radical scavenging activities. Also it appears to inhibit serotonin re-uptake, melanogenesis, inflammation and cytochrome P450 3A4, 2B6, and 2C9.

CHARACTERISTICS

1. Whitening: The inhibitory force to the activity of tyrosinase is stronger than that of the Arbutin,Kojic Acid, Vitamin C and Hydroquinone. It can further inhibit the activity of dopachrome2. Similar activity to SOD: It has the same dispelling force to free oxidizing radical similar to SOD(super oxide dismutase) tautomerase (TRP-2). It possesses a quick and highly effective whitening function.3. Oxygen resistance: It has an approximate resistant force to oxidation as vitamin E.

MOLECULE FORMULA OF ACTIVE INGREDIENT 

C20H20O4

MOLECULE WEIGHT OF ACTIVE INGREDIENT 

324.37

SPECIFICATION

Glabridin PT90

Appearance:Off-white powder

Active ingredient (Glabridin) content (HPLC) :Not less than 90%

Loss on Drying :≤3%

Heavy metals:≤20 ppm 

Arsenic  (As) :≤2ppm

Total bacteria count:Less than 1000 cfu/g

Yeast/moulds:Less than 100 cfu/g

E-Coli:Negative

Salmonella:Negative

Staphylococcus aureus:Negative

Solubility: soluble in ethanol and 1,3-butylene glycol

Particle size: 100% pass 100 mesh

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